This zone makes signaling molecules that stimulate the cell proliferation of the frontonasal process.
2.
FND consists of various nasal malformations that result from excessive tissue in the frontonasal process, which results in hypertelorism and a broad nasal bridge.
3.
The formation of the frontonasal process is the result of a complex signaling system which begins with the synthesis of retinoic acid ( a vitamin A metabolite ).